A new meta-analysis of seven clinical trials shows daily cranberry intake might reduce the risk of recurrent urinary tract infections (rUTI) significantly.
After reviewing scientific literature, researchers chose seven relevant randomized controlled trials for this meta-analysis. In general the studies were fairly small with only 2 of the studies having over 300 participants. Data from almost 1500 women showed a 23% reduction in the risk of rUTI in women with daily cranberry intake. Limited data from various subgroup analyses found supplementation of cranberry capsules or tablets were more effective forms of cranberry intake.
In one specific randomized, double-blind, placebo-controlled multi center clinical trial, over 370 women who experienced a recent history of UTIs were randomly assigned to receive either a 240 ml/day beverage of either cranberry or a placebo. This study lasted 24 weeks. There was a significant reduction seen in investigator-diagnosed episodes of clinical UTI’s in the cranberry group (39) when compared to the placebo group (66).
Women have a 50% risk of having a UTI within her lifetime. It has been estimated that between 20% – 30%of these women will experience recurrent UTIs (rUTIs). The annual healthcare cost of UTIs in women is estimated to be over $2.6 billion.
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