According to a new study in eLife low levels of CoEnzyme Q10 (COQ10) in muscle and fat cells are associated with insulin resistance.
Researchers found a reduction in mitochondrial CoQ10 levels in samples from insulin-resistance humans, mouse modes and in cellular in vitro experiments. The study also found that the reduction in mitochondrial CoQ10 brings about insulin resistance by increasing mitochondrial oxidants. Previous studies have shown that these oxidants can cause insulin resistance.
Researchers also showed CoQ10 supplementation also restored insulin sensitivity and mitochondrial CoQ10 levels, a significant finding for developing programs for treating pre-diabetes and insulin resistance.
CoQ10 is an enzyme found in the cells mitochondria and aids in transferring oxygen between cells. It is recognized as necessary for converting nutrients into usable energy.
Further studies are planned.
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