A new research team has suggested that supplementation with Folic Acid may reduce the risk of stroke by approximately 75% in individuals with High Blood Pressure.
Over 10,750 individuals who were a part of the China Stroke Primary Prevention Trial (CSPPT) participated in this RCT (randomized controlled trial). Participants varied in age from 45 to 75 years of age. All participants had Hypertension or were taking Anti-Hypertensive medication. Participants were randomly assigned into two groups. Group one contained over 5,400 patients who received either a daily 10 mg oral dose of Enalapril, an Anti-Hypertensive, plus 800 mcg of Folic Acid. Group two contained over 5,300 patients who received only the Enalapril.
210 first strokes occurred in group two, the Enalapril only group, while 161 first strokes occurred in group one, the Enalapril plus Folic Acid group over a 4 year period. Researchers determined that the risk of a first stroke was reduced from 5.6% to 1.8% in group one participants who shared low platelet counts and high homocysteine levels which represented a 73% risk reduction. No benefits in Folic Acid supplementation was seen in participants with a high platelet count and low homocysteine levels.
Researchers concluded taking a B Vitamin or a Multi-Vitamin/Mineral Supplement containing Folic Acid was a wise move for all adults.
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