A new study found a Vitamin D deficiency could be associated with a higher ratio of total cholesterol to HDL in addition to lower levels of HDL-cholesterol. This higher ratio of total cholesterol to HDL has been associated with increased cardiovascular risks more than those seen with other cholesterol measures like LDL-cholesterol (often called bad cholesterol).
Data from over 13,000 individuals who participated in the Atherosclerosis Risk in Communities Study (ARIC) was analyzed. The average age of the participants was 57 years of age and the mean Vitamin D level (25(OH)D) was 24 ng/ml. Deficiency of this non active storage form of Vitamin D (25(OH)D) is less than 20 ng/ml however optimal levels of this form of Vitamin D is at least 30 ng/ml.
After adjustments were made for a range of potential confounding variables, individuals with a Vitamin D deficiency had a HDL Cholesterol level approximately 3 mg/dl lower than participants with optimal Vitamin D levels. Additionally the total Cholesterol to HDL was .18 higher in the Vitamin D deficient participants. When individuals on cholesterol lowering therapies were removed from the analysis an association between Vitamin D deficiency and higher LDL cholesterol were also observed.
Researchers believe the major implication of this study is the chance of changing cardiovascular risk factors through Vitamin D supplementation.
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