A new study shows patients with Type 2 Diabetes who are taking statin drugs and supplementing with Vitamin D improves their cardio respiratory fitness as well as muscle mitochondria.
28 individuals participated in this randomized controlled trial. Data from the participants upon completion of the trial showed that participants cardio respiratory fitness decreased by 8.4% after 12 weeks of simvastatin therapy. These individuals also experienced a 3.6% decrease in mitochondrial content. Participants who were taking the simvastatin therapy but were also supplementing with Vitamin D however showed a decrease in cardio respiratory fitness of only .6% and a 12.1% improvement in mitochondrial content. Participants who only took Vitamin D without the simvastatin therapy saw an increase in cardio respiratory fitness of 7.1% and a 16.7% increase in mitochondrial content.
Researchers believe that the statin simvastatin in inclined to cause a decline in exercise-mediated cardio respiratory fitness in adults with Type 2 Diabetes by interrupting the synthesis of CoEnzyme Q10.
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