According to a new study a supplement containing Antioxidants plus Zinc may be a cost effective way to slow down the progression of the wet form of the common degenerative eye disease, Macular Degeneration.
Data from the AREDS study in addition to real world outcomes using the National Health Service EMR, a multicenter Neovascular (wet form) Age Related Macular Degeneraton (nAMD) database, denoting the use of Anti-VEGF injections. These Anti-Vascular Endothelial Growth Factor injections (Anti-VEGF) are the principal medical treatment for the wet form of Age Related Macular Degeneration. These Anti-VEGF injections are costly in addition to possibly increasing inflammation and stroke risk. The study looked at the use of AREDS formulated supplements containing the following:
AREDS1 contains 80 mg Zinc, 2 mg Copper, 500 mg of Vitamin C, 15 mg Beta-Carotene and 400 IU Vitamin E.
AREDS2 reduced the Zinc to 25 mg and removed the Beta-Carotene but added 10 mg of Lutein, 2 mg of Zeaxanthin, and 1000 mg of Omega 3 Essential Fatty Acids.
Using the Markov Model, a statistical method used to predict an outcome between non supplemented and supplemented participants, 5 different states of visual acuity were incorporated into the research. These 5 states cast the progression of the nAMD while projecting the necessity of the Anti-VEGF injections. Estimating the injection costs and the costs of the specialist exams were also added to the economic model.
Researchers determined that supplementation with the AREDS combination was effective in category 3 and category 4 AMD participants. This conclusion was consistent with previous research. Additionally researchers advocated that supplementation was” an attractive strategy to avoid the chronic and costly Anti-VEGF therapies and to preserve visual function”.
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