A new study found oral supplementation with Omega-3 Essential Fatty Acids may help treat and prevent wounds caused by Mucositis (mouth ulcers and inflammation) in cancer patients undergoing chemotherapy. Mucositis is a potential side effect of chemotherapy. An overwhelming number of cancer patients (80%) with neck and head malignancies in addition to cancer patients on a high dose of chemotherapy experience Mucositis. Mucositis is also associated with severe pain, a higher risk of developing systemic and local infections, bleeding and dysfunction from the oral cavity, mouth and pharynx. Oral ulcers may even cause bacteria to enter the blood stream and cause septicemia which especially damaging since patients on chemotherapy usually have compromised immune systems.
60 patients who were developing grade 1 oral Mucositis participated in this Random Controlled study. The participants were divided into 2 groups; an Omega 3 group (12 males and 18 females) and a placebo group (11 males and 19 females). The participants were assessed for Mucositis using the WHO Oral Mucositis Weekly Questionnaire and the Western Consortium for Cancer Nursing Research criteria at the beginning of the trial, in the first, second and third weeks of chemotherapy and when the Mucositis was cured. Using the Oral Mucositis Weekly Questionnaire, researchers noted the differences in the severity of the Mucositis between the 2 groups in the first, second and third week s of the study. The Omega-3 supplementation group had less severe pain during the three weeks of treatment, there actually was no sign Mucositis in the participants supplementing with the Omega 3 after 2 weeks. In the Omega-3 group average recovery was 4 to nine days vs over 10 days in the placebo group, and 12 patients in the placebo group took over 16 days to recover.
Researchers concluded Omega-3 Essential Fatty acids were an effective and safe means for treating and preventing oral Mucositis.
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