A meta analysis was conducted to find out whether Garlic intake could reduce the risk of colorectal and/or gastric cancer. 9 studies looking at Garlic intake and colorectal cancer and 11 studies looking at Garlic and gastric cancers were reviewed.
The 11 studies included almost 3,300 patients with gastric cancer and over 133,000 controls from a randomized controlled trial, 8 case controlled studies, and 2 cohort studies. In 9 of the 11 studies, significant reductions in the incidence of gastric cancers were seen in participants with increased Garlic intake. Researchers believe the organic sulfur compounds found in Garlic, like Allicin are the main components that may produce antitumor activity.
The 9 studies included 7 case controlled studies and 2 cohort studies involving over 8,500 patients with cancer and over 52,000 controls. These 9 studies on Garlic intake showed that Garlic significantly reduced the risk of colorectal cancer. Researchers summarized that the main organic phytonutrients found in Garlic may have contributed to the regulation of tumor cell apoptosis (cell death), cell cycles, and cell migration. This translates into risk reduction of developing gastrointestinal tumors.
To summarize, Garlic with its phytonutrient compounds, like Allicin, may benefit both tumor prevention and other therapeutic benefits which could represent new alternative antitumor treatment.
Further studies are needed.
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