According to a new meta-analysis, daily Vitamin C supplementation may lower levels of LDL Cholesterol by 5%. This reduction in LDL (bad) Cholesterol aids in reducing Cardiovascular Disease risk factors.
Over 400 individuals with High Blood Pressure participated in these 13 randomized clinical studies chosen for this meta-analysis which was published in the Journal of Chiropractic Medicine. The participants received Vitamin C Supplements with at least a potency of 500 mg daily. The studies lasted for a period of 3 to 24 weeks. All the studies were either a placebo-controlled double blind study or a crossover double blind study. The average age of the study participants was 58.9 years of age with 60% of the participants being men.
The results of the studies showed a 7.9 mg per dL reduction in LDL blood levels while HDL (good cholesterol) blood levels increased by 1.1 mg per dL. The HDL blood level increases were not considered to be statistically significant. Vitamin C dosages of at least 500 mg daily were also associated with an 8.8% reduction in Triglyceride levels. It is believed that a reduction in LDL Cholesterol of 7.9 mg per dL could translate into a 6.6% reduction in Coronary Heart Disease and a reduction in Triglyceride levels of 20.1 mg per dL could reduce Coronary Heart Disease risk by 2.4%.
Researchers noted that Vitamin C may intercept ROS (reactive oxygen species), which might inhibit the oxidative modification of LDL Cholesterol. This protection allows the LDL receptors in the liver to recognize LDL Cholesterol and expedite its removal from the blood by LDL Cholesterol catabolic pathways.
Further studies are needed to account for some inconsistencies found in some of the studies, like Vitamin C dosage levels, participants ages and study durations.
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