Gut dysbiosis (when the bacteria in the gut are out of balance) has commonly been associated with aging and the afflictions of aging. Worldwide the implications of aging populations have become a major issue.
Alzheimer’s Disease:
4 bacterial strains common to all participants with Alzheimer’s Disease have been isolated in a recent study on Japanese Alzheimer’s Disease. Studies also have shown reduced gut microbial diversity has been associated with this disease.
Osteoporosis:
Most of the microbiome data for this disease has come from mouse models. A recent study has shown strains of Lactobacillus have been associated with increases in bone mass in addition to changes in the microbiota in the gut. It has also been shown that prebiotics may actually increase Calcium absorption when taken together.
Sarcopenia, CVD Evidence:
There have been certain studies that link the prevention of muscle loss in mice with leukemia and probiotic supplementation. Prebiotics have been shown to improve muscle function in humans when measuring grip strength.
Studies linking gut microbiome to both positive and negative roles in heart disease have been performed. Certain aspects of gut dysbiosis have been linked with increased levels of trimethylamine-N-oxides in the liver which have been known to cause the formation of arterial plague.
Overall it is believed that the combination of lifestyle interventions that change the diversity or composition of gut microbiota, adequate exercise, and proper diet may be a key strategy in the maintenance of good health during the aging process.
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