According to 2 recent studies, Quercetin, a plant-derived antioxidant shows the potential to aid in treating COVID-19.
Study #1:
In this study, published in the International Journal of General Medicine, 42 COVID-19 patients took part in this study. Participants were divided into 2 groups. The first group consisted of 21 patients who were given a standard therapy for COVID-19 treatment (acetaminophen and antibiotics for 2 days). The second group of 21 patients received the standard therapy plus 600 mg of Quercetin daily (divided into 3 doses) for a period of 7 days, followed by an additional 7 days of Quercetin at a 400 mg dosage daily (divided into 2 doses). Researchers were interested in evaluating symptoms and virus clearance.
After 1 week of treatment 16 participants in the Quercetin group tested negative for COVID-19 (SARS-CoV-2) while 12 patients reported that all symptoms of the virus were gone. In the first group who only received the standard therapy only 2 patients tested negative for COVID-19 and 4 reported only a partial improvement in symptoms. By the end of week 2 the 5 remaining participants in the second group (the Quercetin group) tested negative for COVID-19. In group 17 of the remaining 19 participants tested negative for COVID-19 while 1 participant died.
Study #2:
In this randomized, prospective and controlled open-label trial, 152 COVID-19 outpatients received a daily dose of 1000 mg of Quercetin for 30 days. The goal of the study was to evaluate the effects of Quercetin on the treatment of early COVID-19 symptoms as well as the prevention of severe infection.
The results of this study showed a reduction in the length of hospitalization and the frequency of hospitalization as well as the reduction in the need for non-invasive oxygen therapy, the progression to the intensive care unit and in the number of deaths. In addition the Quercetin proved to be highly safe and showed some potential in eliminating fatigue and provides pro- appetite properties.
Researchers from the first study chose to try Quercetin because it has previously been shown to exhibit antioxidant, anti-inflammatory, anti-blood clotting and antiviral properties. All of these benefits have been shown to be important in treating COVID-19 (SARS-CoV-2). Researchers from the second study looked more at specific enzymes and their role in the intricate biochemistry taking place in the fight against COVID-19.
Initially Quercetin gained attention because it shuttles Zinc into the cells. It is common knowledge that Zinc exhibits antiviral properties. Quercetin is characterized by 3 crucial and unique properties: immunomodulatory, anti-inflammatory, and antioxidant. The actions in combination allow Quercetin to be a candidate for helping any unhealthy condition where immunity, inflammation and oxidative stress come into play.
Additionally, Quercetin has shown the ability to block the binding of specific spike proteins to ACE-2 receptors hence blocking the virus’s ability to infect human cells while also neutralizing viral proteins needed for viral replication.
There is a lot more to Quercetin and the research is fairly extensive to the many benefits of this nutrient.
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