A new double blind, placebo-controlled study published in the journal Scientific Reports, found Vitamin D and Resveratrol in combination reduced the hospitalization rate among a group of individuals who tested positive for Covid-19.
100 individuals 45 years and older who had tested positive for Covid-19 were recruited, via cold calls to patients of the Mount Carmel Health System in Columbus, OH, to participate in this study. Vitamin D3, in a single acute dose of 100,000, was administered as an adjunct treatment due to prior research showing its synergistic anti-inflammatory benefits. 500 mg of Resveratrol was given daily to the treatment group for 15 days. The control group received an identical placebo. At the time this research was conducted (2020) the rate of hospitalization among confirmed Covid-19 cases was approximately 21% for individuals in the age group 45-54 years of age and up to 31% for individuals in the age group over 81 years of age.
Researchers found the above outlined intervention cut the hospitalization rate. In the treatment group (50 participants) only 1 participant was hospitalized (2% rate). In the control group 3 participants required hospitalization (6% rate). Additionally the Resveratrol group had 4 visits to the Emergency Room and 4 cases of Pneumonia, and the control group had 7 Emergency Room visits and 8 cases of Pneumonia.
Researchers concluded the antiviral, anti-inflammatory, and antioxidant properties of Resveratrol were largely responsible for the results seen in the study. Resveratrol is a polyphenol found in wine grapes, Japanese knotweed as well as other botanical sources.
Further studies are needed.
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