Cells may be protected from the damaging effects of oxidative stress with daily supplementation of Vitamin E, according to a new study.
180 people between the ages of 55 and 77 participated in this double blind, randomized trial. The study lasted four months. Participants were split into 4 groups. Each person was randomly assigned to receive Vitamin E in doses of 0, 100, 200 or 300 mg.
At the end of the trial, results showed blood levels of alpha tocopherol had increased by 71% for participants receiving 100 mg of Vitamin E, 78% for participants receiving 200 mg of Vitamin E and 95% for participants receiving 300 mg of Vitamin E. Additionally, levels of MDA, (malondialdehyde-a reactive carbonyl compound), a well established marker of oxidative stress, showed significant reductions in the groups of participants receiving the Vitamin E supplement. Erythrocyte hemolysis, an indirect marker of oxidative stress, was also reduced between 20% and 38% in the participants receiving the Vitamin E supplements. The group supplementing the higher doses of Vitamin E had “dramatic improvements in erythrocyte membrane fluidity” according to researchers.
Vitamin E’s antioxidant properties have been well established, however very few studies support the benefits of Vitamin E on the fluidity of the membrane of red blood cells (erythrocytes) and the decreased red blood cell rupturing (erythrocytes hemolysis).
Further research is in the planning stages.
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